Curated Information
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Curated Information Page
PubMed Id: 16603632 
Zhu C, et al. (2006) Spatiotemporal control of spindle midzone formation by PRC1 in human cells. Proc Natl Acad Sci U S A 103, 6196-201 16603632
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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T470-p - PRC1 (human)
Orthologous residues
PRC1 (human): T470‑p, PRC1 iso2 (human): T440‑p, PRC1 iso3 (human): T429‑p, PRC1 (mouse): T470‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  HeLa (cervical)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Effect of modification (process):  cytoskeletal reorganization

T481-p - PRC1 (human)
Orthologous residues
PRC1 (human): T481‑p, PRC1 iso2 (human): T451‑p, PRC1 iso3 (human): T440‑p, PRC1 (mouse): T478‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  HeLa (cervical)
 Cellular systems studied:  cell lines
 Species studied:  human
 Enzymes shown to modify site in vitro
Type Enzyme
PHOSPHATASE CDC14A (human)
KINASE CDK1 (human)
Downstream Regulation
 Effect of modification (process):  cytoskeletal reorganization


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