Curated Information
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Curated Information Page
PubMed Id: 21561859 
Park JH, Arakawa-Takeuchi S, Jinno S, Okayama H (2011) Rho-associated Kinase Connects a Cell Cycle-controlling Anchorage Signal to the Mammalian Target of Rapamycin Pathway. J Biol Chem 286, 23132-41 21561859
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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T508-p - LIMK1 (rat)
Orthologous residues
LIMK1 (human): T508‑p, LIMK1 (mouse): T508‑p, LIMK1 (rat): T508‑p

T389-p - p70S6K iso2 (rat)
Orthologous residues
p70S6K (human): T412‑p, p70S6K iso2 (human): T389‑p, p70S6K (mouse): T412‑p, p70S6K (rat): T412‑p, p70S6K iso2 (rat): T389‑p, p70S6K (fruit fly): T398‑p

S772-p - Rb (rat)
Orthologous residues
Rb (human): S780‑p, Rb (mouse): S773‑p, Rb (rat): S772‑p

S799-p - Rb (rat)
Orthologous residues
Rb (human): S807‑p, Rb (mouse): S800‑p, Rb (rat): S799‑p

S803-p - Rb (rat)
Orthologous residues
Rb (human): S811‑p, Rb (mouse): S804‑p, Rb (rat): S803‑p

T1203-p - TSC2 (rat)
Orthologous residues
TSC2 (human): T1203‑p, TSC2 iso3 (human): T1159‑p, TSC2 iso4 (human): T1203‑p, TSC2 (mouse): T1203‑p, TSC2 iso6 (mouse): T1203‑p, TSC2 (rat): T1203‑p, TSC2 iso2 (rat): T1160‑p
Upstream Regulation
 Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE ROCK1 (human)
Downstream Regulation
 Effect of modification (process):  signaling pathway regulation
 Comments:  activation of mTORC1

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