|
Orthologous residues
|
|
STEP (human): S245‑p, STEP (mouse): S221‑p, STEP (rat): S49‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
mutation of modification site, phospho-antibody
|
|
Relevant cell lines - cell types - tissues:
'neuron, cerebral cortical'-brain
|
|
Cellular systems studied:
primary cultured cells
|
|
Species studied:
rat
|
|
Upstream Regulation
|
|
Treatments, proteins and their effect on site modification:
|
|
Treatments
|
Referenced Treatments
|
Manipulated Protein
|
Referenced Protein
|
Effect
|
Notes
|
|
glutamate
|
|
|
|
decrease
|
|
|
staurosporine
|
|
|
|
decrease
|
|
|
