Curated Information

Javascript is not enabled on this browser. This site will not work properly without Javascript.

Home

Curated Information Page

PubMed Id: 9463386

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Yoneyama M, et al. (1998) Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300. EMBO J 17, 1087-95 9463386

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

S385-p - IRF3 (human)

▲

Orthologous residues

IRF3 (human): S385‑p, IRF3 (mouse): S378‑p, IRF3 (rat): S380‑p

Characterization

Methods used to characterize site in vivo: [32P] bio-synthetic labeling, immunoprecipitation, mutation of modification site, phospho-antibody, phosphoamino acid analysis, phosphopeptide mapping

Relevant cell lines - cell types - tissues: L929 (fibroblast)

Cellular systems studied: cell lines

Species studied: mouse

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
Newcastle disease virus				increase

Downstream Regulation

Effect of modification (function): intracellular localization

S386-p - IRF3 (human)

▲