Curated Information

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Curated Information Page

PubMed Id: 11781828

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Marienfeld R, et al. (2001) Signal-specific and phosphorylation-dependent RelB degradation: a potential mechanism of NF-kappaB control. Oncogene 20, 8142-7 11781828

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

T84-p - RelB (mouse)

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Orthologous residues

RelB (human): T103‑p, RelB (mouse): T84‑p

Characterization

Methods used to characterize site in vivo: [32P] bio-synthetic labeling, electrophoretic mobility shift, mutation of modification site

Disease tissue studied: lymphoma, T cell lymphoma

Relevant cell lines - cell types - tissues: EL-4 (T lymphocyte), Jurkat (T lymphocyte)

Cellular systems studied: cell lines

Species studied: human, mouse

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
phorbol ester, ionomycin				increase

Downstream Regulation

Effect of modification (function): protein degradation

S552-p - RelB (mouse)

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