Yoshihara K, et al. (2011) Phosphorylation state regulates the localization of Scribble at adherens junctions and its association with E-cadherin-catenin complexes. Exp Cell Res 317, 413-22 21146521

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S1601-p - Scribble iso3 (mouse) ▲

Modsite: RPVYDIQsPDFVEEL SwissProt Entrez-Gene Orthologous residues Scribble (human): S1566‑p, Scribble iso2 (human): S1485‑p, Scribble iso3 (human): S1591‑p, Scribble (mouse): S1548‑p, Scribble iso3 (mouse): S1601‑p, Scribble (rat): S1599‑p Characterization Methods used to characterize site in vivo:  electrophoretic mobility shift, immunoprecipitation, mutation of modification site, phospho-antibody, western blotting Disease tissue studied:  breast cancer Relevant cell lines - cell types - tissues:  293 (epithelial), EpH4 (epithelial), L929 (fibroblast) [CDH1 (mouse), transfection], MTD-1A (breast cell) Cellular systems studied:  cell lines Species studied:  human, mouse Downstream Regulation Effect of modification (function):  intracellular localization, molecular association, regulation Effect of modification (process):  cell adhesion, altered Modification regulates interactions with:  Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays CDH1 (mouse) Disrupts co-immunoprecipitation Comments:  interaction with E-cadherin-catenin complex