Curated Information

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Curated Information Page

PubMed Id: 11983165

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Palmer A, et al. (2002) EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Mol Cell 9, 725-37 11983165

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

Y323-p - EFNB1 (mouse)

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Orthologous residues

EFNB1 (human): Y324‑p, EFNB1 (mouse): Y323‑p, EFNB1 (rat): Y323‑p, EFNB1 (chicken): Y312‑p

Characterization

Methods used to characterize site in vivo: [32P] bio-synthetic labeling, phospho-antibody

Relevant cell lines - cell types - tissues: 'neuron, cortical'-brain, 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout]

Cellular systems studied: cell lines, primary cells

Species studied: mouse

Upstream Regulation

Potential in vivo enzymes for site:

Type	Enzyme	Evidence	Notes
KINASE	Src (mouse)	pharmacological inhibitor of upstream enzyme, microscopy-colocalization	A Src-family kinase was implicated

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
EphB1				increase
EphB2				increase
EphB4				increase

Y328-p - EFNB1 (mouse)

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