Curated Information
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Curated Information Page
PubMed Id: 11348595 
Huber AH, Weis WI (2001) The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell 105, 391-402 11348595
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S840-p - CDH1 (mouse)
Orthologous residues
CDH1 (human): S838‑p, CDH1 (mouse): S840‑p, CDH1 (rat): S842‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry (in vitro)
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CK2A1 (human)
 Comments:  S842 and S848 may also be phosphorylated by GSK3B in vitro.
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
CTNNB1 (mouse) Induces affinity chromatography

S842-p - CDH1 (mouse)
Orthologous residues
CDH1 (human): S840‑p, CDH1 (mouse): S842‑p, CDH1 (rat): S844‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry (in vitro)
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CK2A1 (human)
 Comments:  S842 and S848 may also be phosphorylated by GSK3B in vitro.
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
CTNNB1 (mouse) Induces affinity chromatography

S848-p - CDH1 (mouse)
Orthologous residues
CDH1 (human): S846‑p, CDH1 (mouse): S848‑p, CDH1 (rat): S850‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry (in vitro)
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CK2A1 (human)
 Comments:  S842 and S848 may also be phosphorylated by GSK3B in vitro.
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
CTNNB1 (mouse) Induces affinity chromatography


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