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Orthologous residues
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DIXDC1 (human): S224‑p, DIXDC1 (mouse): S250‑p, DIXDC1 iso11 (mouse): S13‑p, DIXDC1 (rat): S229‑p
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Characterization
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Methods used to characterize site in vivo:
immunoprecipitation, mutation of modification site
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Relevant cell lines - cell types - tissues:
293 (epithelial)
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Cellular systems studied:
cell lines
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Species studied:
human
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Enzymes shown to modify site in vitro:
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Downstream Regulation
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Effect of modification (function):
molecular association, regulation
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Effect of modification (process):
cell motility, altered, cytoskeletal reorganization
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Modification regulates interactions with:
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Interacting molecule
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Interacting domains
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Effect
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Consequences (function)
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Consequences (process)
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Detection assays
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NDEL1 (human)
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Induces
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co-immunoprecipitation
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Comments:
DIXDC1/NDEL1/DISC1 complex
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