Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Curated Information Page
PubMed Id: 20869591 
Duvick L, et al. (2010) SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776. Neuron 67, 929-35 20869591
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Download Sites

S751-p - ataxin-1 (mouse)
Orthologous residues
ataxin‑1 (human): S775‑p, ataxin‑1 (mouse): S751‑p, ataxin‑1 (rat): S749‑p
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  'neuron, Purkinje'-'brain, cerebellum'
 Cellular systems studied:  primary cells
 Species studied:  mouse
 Comments:  transgenic mice expressing ATXN1[82Q]-D752
Downstream Regulation
 Effect of modification (process):  apoptosis, altered
 Comments:  S776D mutation initiates neuronal death

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.