Curated Information

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Curated Information Page

PubMed Id: 20682773

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Saxena UH, et al. (2010) Prolyl isomerase Pin1 regulates transcription factor LSF (TFCP2) by facilitating dephosphorylation at two serine-proline motifs. J Biol Chem 285, 31139-47 20682773

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

S291-p - TFCP2 (human)

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Orthologous residues

TFCP2 (human): S291‑p, TFCP2 (mouse): S291‑p

Characterization

Methods used to characterize site in vivo: immunoprecipitation, mutation of modification site

Relevant cell lines - cell types - tissues: 3T3 (fibroblast)

Cellular systems studied: cell lines

Species studied: mouse

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
		Pin1 (human)		decrease

Downstream Regulation

Effect of modification (function): inhibition

Effect of modification (process): transcription, altered

S309-p - TFCP2 (human)

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