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Curated Information Page
PubMed Id: 20736484 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Moritz A, et al. (2010) Akt-RSK-S6 Kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases. Sci Signal 3, ra64 20736484
Only 100 sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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Protein GeneSymb ACC# Organism MW (Da) RSD SiteGrpId Mod Type Site Sequence
53BP2 TP53BP2 Q13625 human 125,616 Y664 450766 Phosphorylation QQHPENIysNsQGKP
Abi-1 ABI1 Q8IZP0 human 55,081 Y23 456322 Phosphorylation KRALIESyQNLTRVA
ACTA1 ACTA1 P68133 human 42,051 Y55 454025 Phosphorylation GMGQkDsyVGDEAQs
ACTG1 ACTG1 P63261 human 41,793 Y240 458084 Phosphorylation sSSLEksyELPDGQV
ALDH9A1 ALDH9A1 P49189 human 53,802 Y476 459562 Phosphorylation NGRVTIEyYSQLKTV
ANXA1 ANXA1 P04083 human 38,714 Y39 455149 Phosphorylation PGsAVsPyPtFNPsS
APLP2 APLP2 Q06481 human 86,956 Y755 454253 Phosphorylation HGyENPtykyLEQMQ
AS160 TBC1D4 O60343 human 146,563 S751 455924 Phosphorylation EGRKRtsstCsNEsL
ATP5H ATP5H O75947 human 18,491 Y150 463024 Phosphorylation TkLDkkkyPyWPHQP
BAG3 BAG3 O95817 human 61,595 Y247 451782 Phosphorylation yQtHQPVyHKIQGDD
BAT2 iso1 PRRC2A P48634 human 228,863 S1085 467536 Phosphorylation APRGRtAsEtRsEGs
BAT2D1 PRRC2C Q9Y520 human 316,911 S1249 471643 Phosphorylation sEtRsEssDFEVVPK
BRAF BRAF P15056 human 84,437 S446 447804 Phosphorylation KtLGRRDssDDWEIP
CAMK2B CAMK2B Q13554 human 72,678 T287 450048 Phosphorylation sMMHRQEtVECLKKF
CAP1 CAP1 Q01518 human 51,901 Y354 463108 Phosphorylation LkQVAyIyKCVNTTL
CASKIN2 CASKIN2 Q8WXE0 human 126,783 Y384 451690 Phosphorylation EPPHPLtysQLPRVG
Catalase CAT P04040 human 59,756 Y84 463116 Phosphorylation KGAGAFGyFEVTHDI
Caveolin-1 CAV1 Q03135 human 20,472 Y14 448422 Phosphorylation VDsEGHLytVPIREQ
Cbl-b CBLB Q13191 human 109,450 Y889 450827 Phosphorylation tNRtsQDyDQLPsCs
CCDC50 CCDC50 Q8IVM0-2 human 56,340 Y455 462101 Phosphorylation tDGEDADytHFtNQQ
CEP170 CEP170 Q5SW79 human 175,293 S1160 457059 Phosphorylation PRRTRLGsLsARsDs
CEP170 CEP170 Q5SW79 human 175,293 S1165 457060 Phosphorylation LGsLsARsDsEATIS
claudin 3 CLDN3 O15551 human 23,319 Y198 461926 Phosphorylation YtATkVVysAPRstG
Cofilin-1 CFL1 P23528 human 18,502 Y140 449641 Phosphorylation HELQANCyEEVkDRC
Cortactin CTTN Q14247 human 61,586 Y178 454843 Phosphorylation kSAVGFDyQGktEKH
Cortactin CTTN Q14247 human 61,586 Y334 450862 Phosphorylation VTQVSSAyQkTVPVE
Cortactin CTTN Q14247 human 61,586 Y433 450411 Phosphorylation sFKAELsyRGPVsGt
Cortactin CTTN Q14247 human 61,586 Y464 450412 Phosphorylation SSQQGLAyATEAVyE
CSTB CSTB P04080 human 11,140 Y97 457987 Phosphorylation AkHDELTyF______
CTAGE5 CTAGE5 O15320 human 90,996 S594 469708 Phosphorylation RAPsDtGsLsPPWDQ
CTNND1 CTNND1 O60716 human 108,170 Y296 450176 Phosphorylation MGyDDLDyGMMsDyG
CTNNG DSP P15924 human 331,774 Y172 451592 Phosphorylation ssKGGGGytCQsGsG
CTNNG DSP P15924 human 331,774 S176 452247 Phosphorylation GGGytCQsGsGWDEF
DBN1 DBN1 Q16643 human 71,429 Y163 458080 Phosphorylation AEPVGTtyQKTdAAV
DDX3 DDX3X O00571 human 73,243 Y69 448982 Phosphorylation ssKDKDAyssFGsRs
Desmoplakin-3 JUP P14923 human 81,745 Y660 459392 Phosphorylation SEDKNPDyRKRVsVE
DLG3 DLG3 Q92796 human 90,314 Y673 451629 Phosphorylation NEVDGQDyHFVVsRE
Dok1 DOK1 Q99704 human 52,392 Y449 448879 Phosphorylation KsHNsALysQVQKSG
DTX2 DTX2 Q86UW9 human 67,246 Y156 463242 Phosphorylation GYNYTVNyTTHTQTN
DYRK1A DYRK1A Q13627 human 85,584 Y145 449566 Phosphorylation DGYDDDNyDyIVKNG
EAP1 IRF2BPL Q9H1B7 human 82,659 S657 449194 Phosphorylation TASARRNsssPVsPA
eEF1A1 EEF1A1 P68104 human 50,141 Y141 451546 Phosphorylation REHALLAytLGVkQL
eEF2K EEF2K O00418 human 82,144 S366 447827 Phosphorylation sPQVRtLsGSRPPLL
EFNB1 EFNB1 P98172 human 38,007 Y329 448343 Phosphorylation GDyGHPVyIVQEMPP
EFNB2 EFNB2 P52799 human 36,923 Y316 447830 Phosphorylation GDyGHPVyIVQEMPP
EGFR EGFR P00533 human 134,277 Y1125 449795 Phosphorylation APsRDPHyQDPHstA
eIF5B EIF5B O60841 human 138,827 S190 452568 Phosphorylation sGEsGDEsDEFLQsR
EMSY EMSY Q7Z589 human 141,468 S209 453526 Phosphorylation RKRRRtNsssssPVV
ENO1 ENO1 P06733 human 47,169 Y287 450348 Phosphorylation yksFIkDyPVVsIED
EPB41L1 EPB41L1 Q9H4G0 human 98,503 Y864 458704 Phosphorylation LVTKAVVyREtDPsP
EphA2 EPHA2 P29317 human 108,266 Y575 454954 Phosphorylation RQsPEDVyFsksEQL
EphA2 EPHA2 P29317 human 108,266 Y628 461992 Phosphorylation AGEFGEVyKGMLKTS
EphA2 EPHA2 P29317 human 108,266 Y772 450861 Phosphorylation EDDPEAtyttsGGkI
EphA5 EPHA5 P54756 human 114,803 Y833 451542 Phosphorylation EDDPEAAyTtRGGKI
EphB4 EPHB4 P54760 human 108,270 Y574 454977 Phosphorylation SNGREAEysDKHGQy
EphB4 EPHB4 P54760 human 108,270 Y596 450855 Phosphorylation VyIDPFtyEDPNEAV
EPS15R EPS15L1 Q9UBC2 human 94,255 Y564 450413 Phosphorylation AHRsLEQyDQVLDGA
Erbin ERBB2IP Q96RT1 human 158,298 Y1107 448973 Phosphorylation PEGDyLsyREFHSAG
ERK2 MAPK1 P28482 human 41,390 Y187 447594 Phosphorylation HtGFLtEyVAtRWyR
Ets-1 ETS1 P14921 human 50,408 S282 449317 Phosphorylation NSLQRVPsyDsFDsE
Ezrin EZR P15311 human 69,413 Y354 448105 Phosphorylation LMLRLQDyEEkTKKA
FAK PTK2 Q05397 human 119,233 Y570 457904 Phosphorylation GDFGLsRyMEDstyy
FAM126A FAM126A Q9BYI3 human 57,625 Y493 465022 Phosphorylation LQEEKLIyVSERTEL
FLNA FLNA P21333 human 280,739 Y1308 464760 Phosphorylation sGNLTETyVQDRGDG
FLNA FLNA P21333 human 280,739 S2152 451357 Phosphorylation TRRRRAPsVANVGsH
FRK FRK P42685 human 58,254 Y387 452029 Phosphorylation KVDNEDIyEsRHEIK
FRS2 FRS2 Q8WU20 human 57,029 Y196 448153 Phosphorylation AEEQVHTyVNTTGVQ
FRS2 FRS2 Q8WU20 human 57,029 Y306 449783 Phosphorylation PSVNKLVyENINGLS
Gab1 GAB1 Q13480 human 76,616 Y406 447946 Phosphorylation DAssQDCyDIPRAFP
GFAT GFPT1 Q06210 human 78,806 S261 467935 Phosphorylation CNLsRVDsttCLFPV
girdin CCDC88A Q3V6T2 human 216,042 Y1799 450762 Phosphorylation QSKDSNPyAtLPRAS
GIT1 GIT1 Q9Y2X7 human 84,341 Y554 449689 Phosphorylation VHVPAGLyRIRKGVs
gp130 IL6ST P40189 human 103,537 Y905 448182 Phosphorylation DEGMPKSyLPQTVRQ
GPR126 GPR126 Q86SQ4 human 136,695 Y1196 462731 Phosphorylation SHTDNVSyEHsFNKS
GRF-1 ARHGAP35 Q9NRY4 human 170,514 Y1105 448941 Phosphorylation RNEEENIysVPHDsT
GSK3A GSK3A P49840 human 50,981 Y279 447723 Phosphorylation RGEPNVsyICsRyyR
GTF3C1 GTF3C1 Q12789 human 238,875 S1068 453791 Phosphorylation NsstDQGsDEEGsLQ
HEC1 NDC80 O14777 human 73,913 Y458 460538 Phosphorylation VKYRAQVyVPLkELL
HER2 ERBB2 P04626 human 137,910 Y1112 448674 Phosphorylation DPsPLQRySEDPTVP
HGK MAP4K4 O95819 human 142,101 S801 454183 Phosphorylation EDTRAAssLNLsNGE
hnRNP H1 HNRNPH1 P31943 human 49,229 Y266 450992 Phosphorylation rFGrDLNyCFSGMsD
Hrs HGS O14964 human 86,192 Y216 450344 Phosphorylation VRVCEPCyEQLNRkA
Hrs HGS O14964 human 86,192 Y237 462241 Phosphorylation TTELPPEyLtsPLsQ
HSP70RY HSPA4 P34932 human 94,331 Y336 450554 Phosphorylation KLKKEDIyAVEIVGG
HSPC227 PDZD11 Q5EBL8 human 16,131 Y10 451588 Phosphorylation SRIPyDDyPVVFLPA
IRS1 IRS1 P35568 human 131,591 S330 447559 Phosphorylation sFRVRAssDGEGTMS
KLC2 KLC2 Q9H0B6 human 68,935 Y345 457366 Phosphorylation GKAEEVEyyyRRALE
lamin A/C LMNA P02545 human 74,139 S390 452605 Phosphorylation EEERLRLsPsPtsQR
lamin A/C LMNA P02545 human 74,139 S414 465834 Phosphorylation sQtQGGGsVtkkRkL
LASS2 CERS2 Q96G23 human 44,876 S341 470692 Phosphorylation KLVEDERsDREEtEs
LASS2 CERS2 Q96G23 human 44,876 S348 469770 Phosphorylation sDREEtEssEGEEAA
LIM PDLIM5 Q96HC4 human 63,945 Y251 449524 Phosphorylation VERytEFyHVPtHsD
LMO7 LMO7 Q8WWI1 human 192,696 S1493 457017 Phosphorylation WIRQRsAsVNKEPVs
LMO7 LMO7 Q8WWI1 human 192,696 Y1672 462447 Phosphorylation QLyCNDCyLRFKSGR
LPP LPP Q93052 human 65,746 Y300 448948 Phosphorylation QGRYYEGyYAAGPGY
LRIG1 LRIG1 Q96JA1 human 119,113 Y941 465270 Phosphorylation CNTEVDCySRGQAFH
MDC1 MDC1 Q14676 human 226,666 S453 453670 Phosphorylation QTTTERDsDTDVEEE
Mena ENAH Q8N8S7 human 66,510 S265 451465 Phosphorylation WERERRIsSAAAPAS
Mer MERTK Q12866 human 110,249 Y754 449990 Phosphorylation KIYSGDYyRQGRIAK
Met MET P08581 human 155,541 Y1234 448470 Phosphorylation RDMYDKEyYSVHNKT

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