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Orthologous residues
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Rad51 (human): Y315‑p, Rad51 (mouse): Y315‑p, Rad51 (rat): Y315‑p
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Characterization
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Methods used to characterize site in vivo:
mutation of modification site, phospho-antibody, western blotting
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Relevant cell lines - cell types - tissues:
32D (myeloid), COS (fibroblast)
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Cellular systems studied:
cell lines
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Species studied:
monkey, mouse
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Upstream Regulation
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Potential in vivo enzymes for site:
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Type
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Enzyme
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Evidence
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Notes
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KINASE
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Bcr/Abl (human)
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microscopy-colocalization, transfection of wild-type enzyme, co-immunoprecipitation, transfection of inactive enzyme, phospho-antibody
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|
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Downstream Regulation
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Effect of modification (process):
apoptosis, altered
|
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Comments:
controls resistance to cisplatin and mitomycin C
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