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Orthologous residues
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MUC1 (human): Y1229‑p, MUC1 iso2 (human): Y238‑p, MUC1 iso6 (human): Y204‑p, MUC1 (mouse): Y604‑p, MUC1 (rat): Y48‑p
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Characterization
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Methods used to characterize site in vivo:
immunoprecipitation, mutation of modification site, phospho-antibody, western blotting
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Relevant cell lines - cell types - tissues:
293 (epithelial), ZR-75-1 (breast cell)
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Cellular systems studied:
cell lines
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Species studied:
human
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Enzymes shown to modify site in vitro:
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Downstream Regulation
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Effect of modification (function):
molecular association, regulation
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Modification regulates interactions with:
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Interacting molecule
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Interacting domains
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Effect
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Consequences (function)
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Consequences (process)
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Detection assays
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|
GSK3B (human)
|
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Disrupts
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CTNNB1 (human)
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Induces
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