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Orthologous residues
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MUC1 (human): S1227‑p, MUC1 iso2 (human): S236‑p, MUC1 iso6 (human): S202‑p, MUC1 (mouse): S602‑p, MUC1 (rat): S46‑p
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Characterization
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Methods used to characterize site in vivo:
[32P] bio-synthetic labeling, immunoprecipitation, mutation of modification site, peptide sequencing, phosphoamino acid analysis
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Relevant cell lines - cell types - tissues:
293 (epithelial), HeLa (cervical)
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Cellular systems studied:
cell lines
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|
Species studied:
human
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Enzymes shown to modify site in vitro:
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Downstream Regulation
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Effect of modification (function):
molecular association, regulation
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Modification regulates interactions with:
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|
Interacting molecule
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Interacting domains
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Effect
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Consequences (function)
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Consequences (process)
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Detection assays
|
|
CTNNB1 (human)
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Disrupts
|
|
|
electrophoretic visualization, co-immunoprecipitation
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|
