Curated Information

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Curated Information Page

PubMed Id: 10748192

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Gamero AM, Larner AC (2000) Signaling via the T cell antigen receptor induces phosphorylation of Stat1 on serine 727. J Biol Chem 275, 16574-8 10748192

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

Y701-p - STAT1 (human)

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Orthologous residues

STAT1 (human): Y701‑p, STAT1 (mouse): Y701‑p, STAT1 (rat): Y701‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody, western blotting

Relevant cell lines - cell types - tissues: Jurkat (T lymphocyte), T lymphocyte-blood

Cellular systems studied: cell lines, primary cells

Species studied: human

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
IFN-alpha				increase
anti-CD3				no change compared to control

S727-p - STAT1 (human)

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