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Orthologous residues
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|
BRIP1 (human): T1133‑p, BRIP1 (mouse): T1130‑p
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|
Characterization
|
|
Methods used to characterize site in vivo:
immunoprecipitation, mutation of modification site, phospho-antibody, western blotting
|
|
Relevant cell lines - cell types - tissues:
293T (epithelial), HeLa (cervical)
|
|
Cellular systems studied:
cell lines
|
|
Species studied:
human
|
|
Downstream Regulation
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|
Effect of modification (function):
molecular association, regulation
|
|
Effect of modification (process):
cell cycle regulation
|
|
Modification regulates interactions with:
|
|
Interacting molecule
|
Interacting domains
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Effect
|
Consequences (function)
|
Consequences (process)
|
Detection assays
|
|
TOPBP1 (human)
|
|
Induces
|
|
|
pull-down assay, co-immunoprecipitation
|
|
