Curated Information

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Curated Information Page

PubMed Id: 20064389

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Lin X, et al. (2009) Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron 64, 807-27 20064389

S129-p - SNCA (human)

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Orthologous residues

SNCA (human): S129‑p, SNCA (mouse): S129‑p, SNCA (rat): S129‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody, western blotting

Relevant cell lines - cell types - tissues: brain [LRRK2 (human), transgenic]

Cellular systems studied: tissue

Species studied: mouse

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
		LRRK2 (human)		decrease	LRRK2 overexpression

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