Curated Information
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Curated Information Page
PubMed Id: 10892742 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Bashaw GJ, et al. (2000) Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor. Cell 101, 703-15 10892742
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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Y1038-p - ROBO1 (human)
Orthologous residues
ROBO1 (human): Y1038‑p, ROBO1 (mouse): Y999‑p, ROBO1 (rat): Y1038‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry (in vitro)
 Relevant cell lines - cell types - tissues:  COS (fibroblast)
 Cellular systems studied:  cell lines
 Species studied:  monkey
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE Abl (human)

Y1073-p - ROBO1 (human)
Orthologous residues
ROBO1 (human): Y1073‑p, ROBO1 (mouse): Y1034‑p, ROBO1 (rat): Y1073‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry (in vitro), mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  COS (fibroblast)
 Cellular systems studied:  cell lines
 Species studied:  monkey
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE Abl (human)
Upstream Regulation
 Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE Abl (human) electrophoretic mobility shift, transfection of wild-type enzyme, mutation in upstream enzyme recognition motif, transfection of constitutively active enzyme
Downstream Regulation
 Effect of modification (function):  activity, inhibited

Y1114-p - ROBO1 (human)
Orthologous residues
ROBO1 (human): Y1114‑p, ROBO1 (mouse): Y1075‑p, ROBO1 (rat): Y1114‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry (in vitro)
 Relevant cell lines - cell types - tissues:  COS (fibroblast)
 Cellular systems studied:  cell lines
 Species studied:  monkey
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE Abl (human)


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