Curated Information

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Curated Information Page

PubMed Id: 11350745

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Benes C, Soltoff SP (2001) Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases. Am J Physiol Cell Physiol 280, C1498-510 11350745

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

T505-p - PKCD (rat)

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Orthologous residues

PKCD (human): T507‑p, PKCD iso13 (human): T507‑p, PKCD (mouse): T505‑p, PKCD iso2 (mouse): T531‑p, PKCD (rat): T505‑p

Characterization

Methods used to characterize site in vivo: immunoprecipitation, phospho-antibody, western blotting

Relevant cell lines - cell types - tissues: parotid acinar-salivary gland

Cellular systems studied: primary cultured cells

Species studied: rat

Enzymes shown to modify site in vitro:

Type	Enzyme
PHOSPHATASE	PTP1B (human)

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
phorbol ester				no change compared to control
phorbol ester, LY294002				no change compared to control
phorbol ester, rapamycin				no change compared to control
LY294002				no change compared to control
rapamycin				no change compared to control
wortmannin				no change compared to control
carbachol				no change compared to control
carbachol				no change compared to control
carbachol				no change compared to control

S662-p - PKCD (rat)

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