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PubMed Id: 17646646 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Huang PH, et al. (2007) Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma. Proc Natl Acad Sci U S A 104, 12867-72 17646646
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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Protein GeneSymb ACC# Organism MW (Da) RSD SiteGrpId Mod Type Site Sequence
Ack TNK2 Q07912 human 114,569 Y518 449530 Phosphorylation GGVKKPtyDPVSEDQ
ACP1 ACP1 P24666 human 18,042 Y132 450718 Phosphorylation QLIIEDPyyGNDsDF
ACTA1 ACTA1 P68133 human 42,051 Y55 454025 Phosphorylation GMGQkDsyVGDEAQs
ANXA2 ANXA2 P07355 human 38,604 Y24 449483 Phosphorylation HstPPsAyGsVkAyt
ANXA2 ANXA2 P07355 human 38,604 Y30 450390 Phosphorylation AyGsVkAytNFDAER
ANXA2 ANXA2 P07355 human 38,604 Y188 455082 Phosphorylation EDGsVIDyELIDQDA
ANXA2 ANXA2 P07355 human 38,604 Y238 450389 Phosphorylation RyKsySPyDMLEsIR
ANXA5 ANXA5 P08758 human 35,937 Y94 457911 Phosphorylation PsRLyDAyELkHALk
ATP6V1E1 ATP6V1E1 P36543 human 26,145 Y56 463029 Phosphorylation QRLKIMEyyEKKEKQ
Axl AXL P30530 human 98,336 Y702 458362 Phosphorylation KKIyNGDyyRQGRIA
calmodulin CALM1 P62158 human 16,838 Y100 448707 Phosphorylation FDkDGNGyIsAAELR
caveolin-1 CAV1 Q03135 human 20,472 Y14 448422 Phosphorylation VDsEGHLytVPIREQ
Cbl CBL P22681 human 99,633 Y700 448529 Phosphorylation EGEEDtEyMtPssRP
CCDC123 CEP89 Q96ST8 human 89,590 Y157 467055 Phosphorylation GGHsDDLyAVPHRNQ
CCDC50 iso2 CCDC50 Q8IVM0 human 35,822 Y144 454595 Phosphorylation TRAyADsyyyEDGGM
CDK2 CDK2 P24941 human 33,930 Y15 447740 Phosphorylation EkIGEGtyGVVykAR
cofilin 1 CFL1 P23528 human 18,502 Y140 449641 Phosphorylation HELQANCyEEVkDRC
CrkL CRKL P46109 human 33,777 Y132 458835 Phosphorylation LEyVRtLyDFPGNDA
CSTB CSTB P04080 human 11,140 Y97 457987 Phosphorylation AkHDELTyF______
Cx43 GJA1 P17302 human 43,008 Y313 454254 Phosphorylation sEQNWANysAEQNRM
DCBLD2 DCBLD2 Q96PD2 human 85,035 Y621 454599 Phosphorylation LQADsAEyAQPLVGG
DCBLD2 DCBLD2 Q96PD2 human 85,035 Y750 454600 Phosphorylation PAPDELVyQVPQSTQ
DDX3 DDX3X O00571 human 73,243 Y104 448983 Phosphorylation DDRGRsDyDGIGsRG
DLG1 DLG1 Q12959 human 100,455 Y760 454924 Phosphorylation yEVDGRDyHFVtsRE
DLG3 DLG3 Q92796 human 90,314 Y673 451629 Phosphorylation NEVDGQDyHFVVsRE
Dok1 DOK1 Q99704 human 52,392 Y362 448367 Phosphorylation DPKEDPIyDEPEGLA
DYRK1A DYRK1A Q13627 human 85,584 Y321 448553 Phosphorylation LGQRIyQyIQsRFYR
EGFR EGFR P00533 human 134,277 Y869 448061 Phosphorylation LGAEEkEyHAEGGKV
EGFR EGFR P00533 human 134,277 Y998 452118 Phosphorylation sPtDsNFyRALMDEE
EGFR EGFR P00533 human 134,277 Y1092 448057 Phosphorylation tFLPVPEyINQsVPK
EGFR EGFR P00533 human 134,277 Y1110 448058 Phosphorylation GsVQNPVyHNQPLNP
EGFR EGFR P00533 human 134,277 Y1138 457950 Phosphorylation tAVGNPEyLNtVQPt
EGFR EGFR P00533 human 134,277 S1162 487358 Phosphorylation AHWAQKGsHQIsLDN
EGFR EGFR P00533 human 134,277 Y1172 448059 Phosphorylation IsLDNPDyQQDFFPk
EGFR EGFR P00533 human 134,277 Y1197 448060 Phosphorylation stAENAEyLRVAPQS
ELMO2 ELMO2 Q96JJ3 human 82,615 Y48 450756 Phosphorylation WSLPNPEyyTLRYAD
ENO3 ENO3 P13929 human 46,932 Y44 458370 Phosphorylation sGAstGIyEALELRD
EPB41L2 EPB41L2 O43491 human 112,588 Y623 450713 Phosphorylation RVEGDNIyVRHsNLM
EPB41L2 EPB41L2 O43491 human 112,588 Y773 459252 Phosphorylation tIREEQEyEEEVEEE
EphA2 EPHA2 P29317 human 108,266 Y575 454954 Phosphorylation RQsPEDVyFsksEQL
EphA2 EPHA2 P29317 human 108,266 Y772 450861 Phosphorylation EDDPEAtyttsGGkI
ERK1 MAPK3 P27361 human 43,136 T202 447542 Phosphorylation HDHtGFLtEyVAtRW
ERK1 MAPK3 P27361 human 43,136 Y204 447543 Phosphorylation HtGFLtEyVAtRWyR
ERK2 MAPK1 P28482 human 41,390 T185 447593 Phosphorylation HDHtGFLtEyVAtRW
ERK2 MAPK1 P28482 human 41,390 Y187 447594 Phosphorylation HtGFLtEyVAtRWyR
Fyn FYN P06241 human 60,762 Y213 451536 Phosphorylation RKLDNGGyyITtRAQ
Gab1 GAB1 Q13480 human 76,616 Y659 447949 Phosphorylation VADERVDyVVVDQQK
GRF-1 ARHGAP35 Q9NRY4 human 170,514 Y1087 449570 Phosphorylation DGFDPsDyAEPMDAV
GRF-1 ARHGAP35 Q9NRY4 human 170,514 Y1105 448941 Phosphorylation RNEEENIysVPHDst
GSK3B GSK3B P49841 human 46,744 Y216 448569 Phosphorylation RGEPNVsyICsRyyR
ITSN2 ITSN2 Q9NZM3 human 193,461 Y968 448979 Phosphorylation REEPEALyAAVNKKP
leupaxin LPXN O60711 human 43,332 Y22 448942 Phosphorylation tLQDsDEysNPAPLP
Met MET P08581 human 155,541 Y1234 448470 Phosphorylation RDMyDkEyysVHNkt
MIG-6 ERRFI1 Q9UJM3 human 50,560 Y394 451607 Phosphorylation KKVsstHyyLLPERP
MIG-6 ERRFI1 Q9UJM3 human 50,560 Y403 477484 Phosphorylation LLPERPPyLDKyEKF
MYL6 MYL6 P60660 human 16,930 Y89 454728 Phosphorylation DQGtyEDyVEGLRVF
N-WASP WASL O00401 human 54,827 Y256 450253 Phosphorylation RETSKVIyDFIEKTG
P130Cas BCAR1 P56945 human 93,372 Y327 448780 Phosphorylation PLLREEtyDVPPAFA
p38-alpha MAPK14 Q16539 human 41,293 Y182 447971 Phosphorylation tDDEMtGyVAtRWYR
PAG PAG1 Q9NWQ8 human 46,981 Y417 448996 Phosphorylation LVPKENDyEsIsDLQ
PIK3CD PIK3CD O00329 human 119,479 Y524 454088 Phosphorylation RRGsGELyEHEKDLV
PIK3R1 PIK3R1 P27986 human 83,598 Y467 451144 Phosphorylation SREyDRLyEEytRTS
PIK3R1 PIK3R1 P27986 human 83,598 Y607 448136 Phosphorylation NENtEDQysLVEDDE
PIK3R2 PIK3R2 O00459 human 81,545 Y464 449572 Phosphorylation sREyDQLyEEytRTS
PIK3R2 PIK3R2 O00459 human 81,545 Y605 451549 Phosphorylation KNEtEDQyALMEDED
PKM2 PKM P14618 human 57,937 Y105 450528 Phosphorylation FAsDPILyRPVAVAL
PKM2 PKM P14618 human 57,937 Y148 454768 Phosphorylation kITLDNAyMEkCDEN
PKM2 PKM P14618 human 57,937 Y175 464024 Phosphorylation VEVGsKIyVDDGLIS
PKM2 PKM P14618 human 57,937 Y390 450529 Phosphorylation REAEAAIyHLQLFEE
PLCG1 PLCG1 P19174 human 148,532 Y771 448575 Phosphorylation IGtAEPdyGALyEGR
PLCG1 PLCG1 P19174 human 148,532 Y1253 448576 Phosphorylation EGsFEsRyQQPFEDF
PRP4 PRPF4B Q13523 human 116,987 Y849 449515 Phosphorylation ADNDItPyLVsRFyR
PTPRA PTPRA P18433 human 90,600 Y798 447613 Phosphorylation yIDAFsDyANFK___
PTRF PTRF Q6NZI2 human 43,476 Y308 450709 Phosphorylation FtPDHVVyARSKtAV
PXN iso2 PXN P49023-2 human 60,967 S84 478263 Phosphorylation IHQQPQsssPVyGss
PXN iso2 PXN P49023-2 human 60,967 Y88 448909 Phosphorylation PQsssPVyGssAKTs
PXN iso2 PXN P49023-2 human 60,967 Y118 448604 Phosphorylation VGEEEHVysFPNKQK
Rin1 RIN1 Q13671 human 84,099 Y36 450778 Phosphorylation kPAQDPLyDVPNAsG
RPS10 RPS10 P46783 human 18,898 Y12 450559 Phosphorylation KKNRIAIyELLFkEG
SCAMP3 SCAMP3 O14828 human 38,287 Y35 451850 Phosphorylation QHRPsRQyAtLdVyN
SgK223 SGK223 Q86YV5 human 149,311 Y411 449701 Phosphorylation ATQPEPIyAEsTKRK
Shb SHB Q15464 human 55,042 Y246 450867 Phosphorylation KVtIADDysDPFDAK
Shb SHB Q15464 human 55,042 Y268 451577 Phosphorylation GKGEsAGyMEPyEAQ
Shb SHB Q15464 human 55,042 Y272 461062 Phosphorylation sAGyMEPyEAQRIMT
Shb SHB Q15464 human 55,042 Y336 451593 Phosphorylation DDRPADEyDQPWEWN
Shc1 SHC1 P29353 human 62,822 Y427 448511 Phosphorylation ELFDDPsyVNVQNLD
SHIP-2 INPPL1 O15357 human 138,599 Y1135 448885 Phosphorylation KtLsEVDyAPAGPAr
SHP-2 PTPN11 Q06124 human 68,436 Y62 449573 Phosphorylation KIQNtGDyyDLyGGE
SHP-2 PTPN11 Q06124 human 68,436 Y546 448492 Phosphorylation SKRKGHEytNIKysL
SLC38A2 SLC38A2 Q9HAV3 human 56,026 Y41 455163 Phosphorylation QAALksHyADVDPEN
Src SRC P12931 human 59,835 Y419 448234 Phosphorylation RLIEDNEytARQGAK
STAT3 STAT3 P40763 human 88,068 Y705 448192 Phosphorylation DPGsAAPyLktKFIC
STAT3 iso2 STAT3 P40763-2 human 87,981 Y704 448192 Phosphorylation ADPGAAPyLKtKFIC
talin 1 TLN1 Q9Y490 human 269,767 Y70 450384 Phosphorylation EAGKALDyyMLRNGD
Tara TRIOBP Q9H2D6 human 261,376 Y1945 451633 Phosphorylation GQRQALDyVELsPLT
Tara TRIOBP Q9H2D6 human 261,376 Y2325 459523 Phosphorylation sGKyQDVyVELSHIK
TfR TFRC P02786 human 84,871 Y20 448928 Phosphorylation FGGEPLsytRFsLAR
TUBA3C TUBA3C Q13748 human 49,960 Y282 459609 Phosphorylation VIsAEkAyHEQLsVA
vigilin HDLBP Q00341 human 141,456 Y437 450572 Phosphorylation DLINRMDyVEINIDH

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