Curated Information
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Curated Information Page
PubMed Id: 10951572 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Lopez-Borges S, Lazo PA (2000) The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein. Oncogene 19, 3656-64 10951572
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T18-p - p53 (mouse) ▲
Orthologous residues
p53 (human): T18‑p, p53 (mouse): T18‑p, p53 iso2 (mouse): T21‑p, p53 (rat): T18‑p, p53 (rabbit): T18‑p, p53 (monkey): T18‑p
Characterization
 Enzymes shown to modify site in vitro: 
Type Enzyme
KINASE VRK1 (human)


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