Curated Information
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PubMed Id: 17213819 
Schild-Poulter C, et al. (2007) DNA-PK phosphorylation sites on Oct-1 promote cell survival following DNA damage. Oncogene 26, 3980-8 17213819
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S78-p - Oct1 (human)
Orthologous residues
Oct1 (human): S78‑p, Oct1 iso5 (human): S101‑p, Oct1 (mouse): S78‑p, Oct1 iso2 (mouse): S78‑p, Oct1 iso12 (mouse): S100‑p, Oct1 (rat): S101‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

S81-p - Oct1 (human)
Orthologous residues
Oct1 (human): S81‑p, Oct1 iso5 (human): S104‑p, Oct1 (mouse): S81‑p, Oct1 iso2 (mouse): S81‑p, Oct1 iso12 (mouse): S103‑p, Oct1 (rat): S104‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

S85-p - Oct1 (human)
Orthologous residues
Oct1 (human): S85‑p, Oct1 iso5 (human): S108‑p, Oct1 (mouse): S85‑p, Oct1 iso2 (mouse): S85‑p, Oct1 iso12 (mouse): S107‑p, Oct1 (rat): S108‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

S88-p - Oct1 (human)
Orthologous residues
Oct1 (human): S88‑p, Oct1 iso5 (human): S111‑p, Oct1 (mouse): S88‑p, Oct1 iso2 (mouse): S88‑p, Oct1 iso12 (mouse): S110‑p, Oct1 (rat): S111‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

S92-p - Oct1 (human)
Orthologous residues
Oct1 (human): S92‑p, Oct1 iso5 (human): S115‑p, Oct1 (mouse): S93‑p, Oct1 iso2 (mouse): S93‑p, Oct1 iso12 (mouse): S115‑p, Oct1 (rat): S115‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

T100-p - Oct1 (human)
Orthologous residues
Oct1 (human): T100‑p, Oct1 iso5 (human): T123‑p, Oct1 (mouse): T101‑p, Oct1 iso2 (mouse): T101‑p, Oct1 iso12 (mouse): T123‑p, Oct1 (rat): T123‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

S141-p - Oct1 (human)
Orthologous residues
Oct1 (human): S141‑p, Oct1 iso5 (human): , Oct1 (mouse): S142‑p, Oct1 iso2 (mouse): S142‑p, Oct1 iso12 (mouse): S164‑p, Oct1 (rat): S164‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

S143-p - Oct1 (human)
Orthologous residues
Oct1 (human): S143‑p, Oct1 iso5 (human): , Oct1 (mouse): S144‑p, Oct1 iso2 (mouse): S144‑p, Oct1 iso12 (mouse): S166‑p, Oct1 (rat): S166‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

S147-p - Oct1 (human)
Orthologous residues
Oct1 (human): S147‑p, Oct1 iso5 (human): , Oct1 (mouse): S148‑p, Oct1 iso2 (mouse): S148‑p, Oct1 iso12 (mouse): S170‑p, Oct1 (rat): S170‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

T162-p - Oct1 (human)
Orthologous residues
Oct1 (human): T162‑p, Oct1 iso5 (human): , Oct1 (mouse): T163‑p, Oct1 iso2 (mouse): T163‑p, Oct1 iso12 (mouse): T185‑p, Oct1 (rat): T185‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

S167-p - Oct1 (human)
Orthologous residues
Oct1 (human): S167‑p, Oct1 iso5 (human): , Oct1 (mouse): S168‑p, Oct1 iso2 (mouse): S168‑p, Oct1 iso12 (mouse): S190‑p, Oct1 (rat): S190‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

T226-p - Oct1 (human)
Orthologous residues
Oct1 (human): T226‑p, Oct1 iso5 (human): T186‑p, Oct1 (mouse): T227‑p, Oct1 iso2 (mouse): T227‑p, Oct1 iso12 (mouse): T249‑p, Oct1 (rat): T249‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)

S232-p - Oct1 (human)
Orthologous residues
Oct1 (human): S232‑p, Oct1 iso5 (human): S192‑p, Oct1 (mouse): S233‑p, Oct1 iso2 (mouse): S233‑p, Oct1 iso12 (mouse): S255‑p, Oct1 (rat): S255‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  MEF (fibroblast) [IGF1R (mouse)]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE DNAPK (human)


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