Curated Information
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Curated Information Page
PubMed Id: 17389604 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
Bassermann F, et al. (2007) Multisite phosphorylation of nuclear interaction partner of ALK (NIPA) at G2/M involves cyclin B1/Cdk1. J Biol Chem 282, 15965-72 17389604
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S354-p - NIPA (human) ▲
Orthologous residues
NIPA (human): S354‑p, NIPA (mouse): S353‑p, NIPA (rat): S353‑p
Characterization
 Methods used to characterize site in vivo:  flow cytometry, immunoprecipitation, mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  HeLa (cervical)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Effect of modification (process):  cell cycle regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
SKP1A (human) Disrupts co-immunoprecipitation

S359-p - NIPA (human) ▲
Orthologous residues
NIPA (human): S359‑p, NIPA (mouse): S358‑p, NIPA (rat): S358‑p
Characterization
 Methods used to characterize site in vivo:  flow cytometry, immunoprecipitation, mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  HeLa (cervical)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Effect of modification (process):  cell cycle regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
SKP1A (human) Disrupts co-immunoprecipitation

S370-p - NIPA (human) ▲
Orthologous residues
NIPA (human): S370‑p, NIPA (mouse): S369‑p, NIPA (rat): S369‑p
Characterization
 Methods used to characterize site in vivo:  flow cytometry, immunoprecipitation, mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  HeLa (cervical)
 Cellular systems studied:  cell lines
 Species studied:  human

S395-p - NIPA (human) ▲
Orthologous residues
NIPA (human): S395‑p, NIPA (mouse): S394‑p, NIPA (rat): S394‑p
Characterization
 Methods used to characterize site in vivo:  flow cytometry, immunoprecipitation, mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  HeLa (cervical)
 Cellular systems studied:  cell lines
 Species studied:  human
 Enzymes shown to modify site in vitro: 
Type Enzyme
KINASE CDK1 (human)
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Effect of modification (process):  cell cycle regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
SKP1A (human) Disrupts co-immunoprecipitation


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