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Orthologous residues
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SH3RF1 (human): S304‑p, SH3RF1 (mouse): S304‑p, SH3RF1 iso2 (mouse): S274‑p, SH3RF1 (rat): S305‑p
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Characterization
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Methods used to characterize site in vivo:
mass spectrometry (in vitro), mutation of modification site
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Disease tissue studied:
breast cancer
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Relevant cell lines - cell types - tissues:
MDA-MB231 (breast cell)
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Cellular systems studied:
cell lines
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Species studied:
human
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Enzymes shown to modify site in vitro:
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|
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Downstream Regulation
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Effect of modification (function):
molecular association, regulation
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Effect of modification (process):
apoptosis, inhibited
|
|
Modification regulates interactions with:
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|
Interacting molecule
|
Interacting domains
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Effect
|
Consequences (function)
|
Consequences (process)
|
Detection assays
|
|
Rac1 (human)
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Induces
|
molecular association, regulation
|
apoptosis, inhibited
|
co-immunoprecipitation
|
|
