Curated Information
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Curated Information Page
PubMed Id: 9384584 
Kato Y, et al. (1997) BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C. EMBO J 16, 7054-66 9384584
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
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S387-p - MEF2C iso3 (human)
Orthologous residues
MEF2C (human): S419‑p, MEF2C iso3 (human): S387‑p, MEF2C iso6 (human): S409‑p, MEF2C (mouse): S420‑p, MEF2C iso4 (mouse): S378‑p, MEF2C (rat): S441‑p
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE ERK5 (human)
Upstream Regulation
 Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE ERK5 (human)
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
serum increase
Downstream Regulation
 Effect of modification (function):  activity, induced
 Comments:  MEF2C activation leads to increased transcription of the c-jun gene.

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