Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Curated Information Page
PubMed Id: 11383510 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Butt E, et al. (2001) Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants. J Biol Chem 276, 7108-13 11383510
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
Download Sites

S15-p - HSP27 (human)
Orthologous residues
HSP27 (human): S15‑p, HSP27 (mouse): S15‑p, HSP27 (rat): S15‑p, HSP27 (pig): S15‑p, HSP27 (hamster): S15‑p, HSP27 (chicken): S15‑p, HSP27 (dog): S15‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE MAPKAPK2 (human)
KINASE PKG1 iso2 (human)
Downstream Regulation
 Effect of modification (process):  cytoskeletal reorganization

S78-p - HSP27 (human)
Orthologous residues
HSP27 (human): S78‑p, HSP27 (mouse): N82‑p, HSP27 (rat): N82‑p, HSP27 (pig): S80‑p, HSP27 (hamster): N86‑p, HSP27 (chicken): S77‑p, HSP27 (dog): S82‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (human)
KINASE MAPKAPK2 (human)
KINASE PKG1 iso2 (human)
Downstream Regulation
 Effect of modification (process):  cytoskeletal reorganization

S82-p - HSP27 (human)
Orthologous residues
HSP27 (human): S82‑p, HSP27 (mouse): S86‑p, HSP27 (rat): S86‑p, HSP27 (pig): S84‑p, HSP27 (hamster): S90‑p, HSP27 (chicken): S80‑p, HSP27 (dog): S86‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE MAPKAPK2 (human)
KINASE PKACA (human)
KINASE PKG1 iso2 (human)
Downstream Regulation
 Effect of modification (process):  cytoskeletal reorganization

T143-p - HSP27 (human)
Orthologous residues
HSP27 (human): T143‑p, HSP27 (mouse): T147‑p, HSP27 (rat): T147‑p, HSP27 (pig): T145‑p, HSP27 (hamster): T151‑p, HSP27 (chicken): T141‑p, HSP27 (dog): T147‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (human)
KINASE PKG1 iso2 (human)


Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.