Curated Information
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Curated Information Page
PubMed Id: 10574913 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Pitcher JA, et al. (1999) Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. J Biol Chem 274, 34531-4 10574913
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S670-p - GRK2 (cow) ▲
Orthologous residues
GRK2 (human): S670‑p, GRK2 (mouse): S670‑p, GRK2 (rat): S670‑p, GRK2 (cow): S670‑p
Characterization
 Methods used to characterize site in vivo:  mass spectrometry, mutation of modification site
 Relevant cell lines - cell types - tissues:  SF9
 Cellular systems studied:  cell lines
 Species studied:  insect
 Enzymes shown to modify site in vitro: 
Type Enzyme
KINASE ERK1 (human)
Downstream Regulation
 Effect of modification (function):  inhibition


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