Curated Information
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Curated Information Page
PubMed Id: 9334404 
Kwon YK, et al. (1997) Activation of ErbB2 during wallerian degeneration of sciatic nerve. J Neurosci 17, 8293-9 9334404
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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T688-p - HER2 (rat)
Orthologous residues
HER2 (human): T686‑p, HER2 iso2 (human): T76‑p, HER2 (mouse): T687‑p, HER2 (rat): T688‑p

Y1223-p - HER2 (rat)
Orthologous residues
HER2 (human): Y1221‑p, HER2 iso2 (human): Y611‑p, HER2 (mouse): Y1222‑p, HER2 (rat): Y1223‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody
 Relevant cell lines - cell types - tissues:  Schwann
 Cellular systems studied:  primary cells
 Species studied:  rat
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
nerve damage increase

Y1224-p - HER2 (rat)
Orthologous residues
HER2 (human): Y1222‑p, HER2 iso2 (human): Y612‑p, HER2 (mouse): Y1223‑p, HER2 (rat): Y1224‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody
 Relevant cell lines - cell types - tissues:  Schwann
 Cellular systems studied:  primary cells
 Species studied:  rat
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
nerve damage increase

Y1250-p - HER2 (rat)
Orthologous residues
HER2 (human): Y1248‑p, HER2 iso2 (human): Y638‑p, HER2 (mouse): Y1249‑p, HER2 (rat): Y1250‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody
 Relevant cell lines - cell types - tissues:  G8/DHFR (fibroblast), Schwann
 Cellular systems studied:  cell lines, primary cells
 Species studied:  mouse, rat
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
nerve damage increase
phorbol ester decrease


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