Curated Information

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Curated Information Page

PubMed Id: 9334404

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Kwon YK, et al. (1997) Activation of ErbB2 during wallerian degeneration of sciatic nerve. J Neurosci 17, 8293-9 9334404

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

T688-p - HER2 (rat)

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Orthologous residues

HER2 (human): T686‑p, HER2 iso2 (human): T76‑p, HER2 (mouse): T687‑p, HER2 (rat): T688‑p

Y1223-p - HER2 (rat)

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Orthologous residues

HER2 (human): Y1221‑p, HER2 iso2 (human): Y611‑p, HER2 (mouse): Y1222‑p, HER2 (rat): Y1223‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody

Relevant cell lines - cell types - tissues: Schwann

Cellular systems studied: primary cells

Species studied: rat

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
nerve damage				increase

Y1224-p - HER2 (rat)

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Orthologous residues

HER2 (human): Y1222‑p, HER2 iso2 (human): Y612‑p, HER2 (mouse): Y1223‑p, HER2 (rat): Y1224‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody

Relevant cell lines - cell types - tissues: Schwann

Cellular systems studied: primary cells

Species studied: rat

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
nerve damage				increase

Y1250-p - HER2 (rat)

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Orthologous residues

HER2 (human): Y1248‑p, HER2 iso2 (human): Y638‑p, HER2 (mouse): Y1249‑p, HER2 (rat): Y1250‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody

Relevant cell lines - cell types - tissues: G8/DHFR (fibroblast), Schwann

Cellular systems studied: cell lines, primary cells

Species studied: mouse, rat

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
nerve damage				increase
phorbol ester				decrease

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