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Orthologous residues
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|
KCNJ12 (human): S431‑p, KCNJ12 (mouse): S425‑p, KCNJ12 (rat): S425‑p
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Characterization
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|
Methods used to characterize site in vivo:
immunoprecipitation, western blotting
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|
Relevant cell lines - cell types - tissues:
'brain, cerebellum', COS (fibroblast), glial, myocyte-heart
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|
Cellular systems studied:
cell lines, primary cells, tissue
|
|
Species studied:
monkey, rat
|
|
Enzymes shown to modify site in vitro:
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|
|
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Downstream Regulation
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|
Effect of modification (function):
molecular association, regulation
|
|
Modification regulates interactions with:
|
|
Interacting molecule
|
Interacting domains
|
Effect
|
Consequences (function)
|
Consequences (process)
|
Detection assays
|
|
DLG1 (rat)
|
PDZ
|
Disrupts
|
molecular association, regulation
|
|
microscopy-colocalization, co-immunoprecipitation, pull-down assay
|
|
