Litjens SH, et al. (2005) Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin. J Biol Chem 280, 22270-7 15817481

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S1325-p - ITGB4 (human) ▲

Modsite: tQPKRPMsIPIIPDI SwissProt Entrez-Gene Orthologous residues ITGB4 (human): S1325‑p, ITGB4 iso2 (human): S1325‑p, ITGB4 iso3 (human): S1325‑p, ITGB4 (mouse): S1327‑p, ITGB4 iso2 (mouse): S1327‑p, ITGB4 iso3 (mouse): S1327‑p, ITGB4 (rat): S1327‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Disease tissue studied:  PA-JEB Relevant cell lines - cell types - tissues:  PA-JEB (keratinocyte) Cellular systems studied:  cell lines Species studied:  human Downstream Regulation Effect of modification (function):  molecular association, regulation Modification regulates interactions with:  Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays Plectin-1 (human) Induces intracellular localization microscopy-colocalization, pull-down assay