Curated Information
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Home > Curated Information Page > PubMed Id: 15916959
Höning S, et al. (2005) Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2. Mol Cell 18, 519-31 15916959
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T156-p - AP2M1 (rat)
Modsite: SQITSQVtGQIGWRR SwissProt Entrez-Gene
Orthologous residues
AP2M1 (human): T156‑p, AP2M1 iso2 (human): T154‑p, AP2M1 (mouse): T156‑p, AP2M1 iso3 (mouse): T154‑p, AP2M1 (rat): T156‑p
Downstream Regulation
Effect of modification (function):  molecular association, regulation, protein conformation
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
TGOLN2 (human) Induces plasmon resonance
Comments:  increased binding to Yxx(hydrophobic) peptides such as TGOLN2 sorting signal (DYQRLN) and to phospholipids (PtdIns4,5P2-containing liposomes)